Endocrine Abstracts

Background: Phosphoprotein enriched in diabetes (PED) is a scaffold protein widely produced in different tissues; it is involved in multiple cellular functions, including insulin-regulated glucose transport. Previous findings showed that in individuals with type 2 diabetes (T2D) the PED gene is overexpressed in skeletal muscle (SM) and adipose tissue (AT), both target tissues for insulin activity. Our group has recently evidenced that PED protein is also expressed in periphera...